Aloe vera lu hui is well known for its considerable medicinal properties. The plant system, therefore, was selected for fabrication of silver. Experts agree that aloe poly acetyl mannans is the active ingredient in aloe vera l aloe barbadensis miller. Potential antibacterial activity of crude extracts from aloe. Sibr aloe vera and its therapeutic efficacy described in. B 4 determination of total phenolic content and antioxidant activity of ethanol extracts from aloe spp.
The present study reports biologically oriented process for green synthesis of cuo nanoparticles by using ecofriendly and nontoxic aloe vera leaf extract. This article is confined to literature pertaining to. Antimicrobial effects of aloe vera on some human pathogens. The first method was developed in a regular reverse phase chromatographic system using a particulate reverse phase c18 column. Isolation, purification and evaluation of antibacterial. Determination of total phenolic content and antioxidant activity of ethanol extracts from aloe spp. Aloe vera is one of the plants exhibiting multiple benefits and has gained considerable importance in.
Materials and methods preparation of aqueous extract of aloe vera aloe vera plant was obtained from the department of agronomy, university of ibadan, ibadan, nigeria. The science of aloe vera and health more about aloesorb aloesorb is a patentpending process that isolates the high molecular weight aloe polysaccharides and infuses them back into our products at 60mg per 2 ounce serving. Pdf antifungal activity of aloe vera gel against plant. Abstractaloe vera, commonly known as barbados or curacao aloe, is an herbal medicine with a long tradition of use by a variety of cultures. Earlier studies have reported the antiinflammatory and antibacterial properties of aloe. Green synthesis of copper oxide nanoparticles using aloe vera leaf extract and its antibacterial activity against fish bacterial pathogens. Medicated plants have major impact on the daytoday life.
Aloe vera injection is to be avoided because of having fatalities. A recent report has shown that the organic extracts of. Aloe vera is a traditional medicinal plant that is harvest in south area ofiran and other regions. Chemical and physical properties of aloe vera aloe barbadensis. Potential candidate in health management via modulation. Medicinal applications and toxicological activities of. Aloe vera specifically refers to the aloe barbadensis miller plant, which is the most common form used in aloebased products. The efficacy of the aloe gel checked in hyperlipidemic type 2 diabetic patients showed reduction in total cholesterol and ldl levels significantly huseini et. Full length research article consumption of aqueous. The succulent plant grows in arid and subtropical climates and is best known for 2 distinct preparations. College of agriculture, sardarkrushinagar dantiwada agricultural university, sardarkrushinagar385506, gujarat, india. Wells of 5 mm diameter were cut on sterile nutrient agar plates and swabbed with an overnight broth culture of the organism.
The results showed that threeyearold aloe vera contained significantly higher levels of polysaccharides and flavonoids than two and fouryearold aloe vera, and no significant differences in flavonoid levels were found between three and fouryearold aloe vera. Evaluation of antioxidant potential of aloe vera aloe. Aloe barbadensis miller is a perennial succulent xerophyte, which develops water storage tissue in the leaves to survive in dry areas of low or erratic rainfall. The aim of this study was to evaluate the antimicrobial efficacy of aloe vera and to determine its effectiveness in decontaminating gutta percha cones. Natural products insider all eyes on aloe pdf lewis je, mcdaniel hr, et. Potential antibacterial activity of crude extracts from. Full length research article consumption of aqueous extract. Chemical and physical properties of aloe vera aloe. Aloe vera exhibits a variety of pharmacological properties antioxidant, antimicrobial, anticancer, immunomodulatory, hyperglycemic, wound healing, hyperlipidemic and antidiabetic. It is difficult to pinpoint exactly where this plant originates from, because it is now found in so many different parts of the world, but many believe that it is native to the deserts of africa and was taken from these deserts to the entire world. Jun 04, 2019 aloe vera has a surprisingly wide footprint when it comes to where it grows and where it is used for medicinal purposes. Ligin this cellulose substance is found in the gel has no known medical properties except it posses the property of penetrating the human skin.
Before that, analysis of aloe vera gel revealed that it has glucomannans, acemmanan, carboxypeptidase, salicylates, and thromboxane inhibitors. Aloe vera, antimicrobial, antibiotics, skin infections, karachi. Antimicrobial activity and phytochemical screening of aloe vera aloe barbadensis miller darshan dharajiya1, nalin pagi2, hitesh jasani3 and payal patel4 1department of plant molecular biology and biotechnology, c. Comparative in vivo and in vitro studies amira mourad hussein aboyoussef, basim anwar shehata messiha department of pharmacology and toxicology, faculty of pharmacy, benisueif university, egypt. Aloe vera may have an additive or a synergistic relationship with over 100 compounds to produce biological activity. These types of plant are effectively and economically, which are adopted in different field of science and technology.
The discussion shows that its physically, biologically and chemically suitable in many applications. Scientific investigations on aloe vera have gained more attention over the last several decades due to its reputable medicinal properties. Determination of total phenolic content and antioxidant. Since 1930, aloe vera gel has been used in clinical practices. Aloe vera linne or aloe barbadensis miller is a succulent from the aloe family 400 different species with its origin in african continent. Antibacterial activity of aloe vera leaf gel extracts against staphylococcus aureus. Beneficial effects of aloe vera in treatment of diabetes. Comparative study of antimicrobial activities of aloe vera. We also studied the capacity of the aqueous extract to inhibit cyclooxygenase activity. Medicinal applications and toxicological activities of aloe. This plant is one of the richest natural sources of health for human beings coming. Improved chromatographic methods for determination of. The extracts were prepared by the sequential cold maceration method by using hexane, ethyl acetate, methanol and distilled water as a solvent.
Aloe vera specifically refers to the aloe barbadensis miller plant, which is the most common form used in aloe based products. Negative effects of aloe vera gel on paracetamolinduced. The anthraquinones and chro mones are responsible for the anticancer activity, anti. Aloe vera is approved by the food and drug administration as a food additive for flavor. Aloe vera has been used from time immemorial for the treatment of a multitude of ailments ranging from peptic ulcers to its use in cosmetics. In vitro and in vivo antioxidant activities of polysaccharide. Aloe vera gel benefits a number of things to hair, including improved detangling, moisture, dandruff soothing, restored ph levels, decreased frizz, enhanced cellular regeneration, antiinflammatory action for the scalp and generation of hair growth. Aloe vera gel as a traditional and complementary method. Aloe vera, nervous system, immuneboosting, antiviral properties. Antibacterial activities and antioxidant capacity of aloe vera. Methods already published were used as a starting point for the development of the new method.
The effect of aloe vera gel on paracetamol induced liver injury in rats was studied using male wistar rats divided into four groups. Aloe vera and gi tract health pdf aloe vera and skin care pdf aloe vera for pet health pdf bioactivity and aloe poly acetyl mannans pdf myths and methodology of aloe vera pdf highest quality aloe vera made. The sterile nutrient agar plates and potato dextrose agar plates were prepared. There are at least 420 different plant species of aloe. Evaluation of antimicrobial activity and cell viability of. Vera juice possessed stronger radical scavenging activity than that of aloe vera powder, and the antioxidative effect of aloe vera extracts was correlated to its development stage 12. The antibacterial activity of aloe vera gel extract was tested using agar well diffusion technique as described by. Aloin and saponin and chemical omposition of volatile. The aim of this study was to identify, quantify, and compare the phytochemical contents, antioxidant capacities, and antibacterial activities of aloe vera lyophilized leaf gel lge and 95% ethanol leaf gel extracts elge using gcms and spectrophotometric methods. Aloe vera is also used in traditional medicine for the treatment of cuts, burns and eczema.
The healthy effect of aloe vera is primarily attributed to the polysaccharides contained in the gel of the leaves. The main aim of this study was to find antimicrobial activity of aloe vera and to find. The antimicrobial activity of aloe vera extract was tested against pathogenic bacteria like. The present investigation was aimed to examine the antimicrobial potential of dmso crude extracts of aloe barbadensis miller aloe vera gel against the selected pathogens bacillus subtilis, salmonella typhi, escherichia coli. Aloe vera on some human pathogens such as escherichia coli, staphylococcus aureus and candida albicans. It is also placed by most sources in the liliaceae family although it has been designated its own family, known as aloeaceae eshun. In addition, aloe vera can be used as a support for drug transport. Aloe is a succulent plant widely used in alternative medicine. Aloe vera has earned its name in many jamaican households as the magic plant often leading the treatment options for a plethora of body, hair and skin conditions because of its proven natural. And to determine the most sensitive to the plant extract amongst the selected test microorganisms.
In this work three chromatographic methods were developed to reduce the total time of the analysis of main compounds in aloe vera extracts. Aloe vera is well known for its succulent leaves and. The main objectives for this study to determine the antimicrobial activity of aloe vera gel. The plant is the source of two products, gel and latex, which are obtained from its fleshy leaves. And to determine the most sensitive to the plant extract. There is no guarantee of strength, purity, or safety of these products. The high of antioxidant activity from a plant was affected by the content of phenolic compounds. Potential antibacterial activity of crude extracts from aloe vera, zingiber officinale and vinca major medicinal plants yisehak tsegaye redda, eyosyas kebede, cruz cruz, getachew gugsa, nesibu awol and brahan mengeste mekelle university college of veterinary medicine, p. Journal of environmental science and health, part c. Antibacterial activity of the extracts was evaluated by using paper disc agar diffusion method. Enzymatic extracts were prepared from aloe vera gel by using ten digestive enzymes including.
A concentrated extract of aloe vera was used to check for the antimicrobial efficacy using the agar. Group 1 control received 50% sucrose orally twice daily for 2 days. Aloe vera contains several groups of chemical constituents such as steroidal lactones, alkaloids. A consumer taking products enhanced with aloesorb receive the maximum benefits for digestive. The implication of unguided human consumption of a. Aloe vera aloe barbadensis miller is a perennial plant of the xanthorrhoeaceae family united, 2012. Antimicrobial activity and phytochemical screening of aloe. The innermost part of the leaf is a clear, soft, moist, and slippery tissue that consists of large thinwalled parenchyma cells in which water is held in the form of a viscous mucilage. Aloe vera is a dietary supplement and not a regulated drug. Invitro antioxidant activity of aloe vera aloe barbadensis. The polysaccharide and flavonoid concentrations of two, three, and fouryearold aloe vera were determined, and their antioxidant activities were evaluated compared to bht and. The comparative antimicrobial activities of the gel and leaf of aloe vera were tested against staphylococcus aureus, pseudomonas aeruginosa, trichophyton mentagraphytes, t. Our objective is to evaluate antimicrobial activity and cytotoxicity of sponges of aloe vera l.
Aloe vera shows antimicrobial activity by rupturing bacterial cell walls. Antiinflammatory activity of extracts from aloe vera gel. All the aloe extracts showed significant antioxidant activity. It has a wellestablished antimicrobial activity ascribed to compounds that are now specifically identified as p coumaric acid, ascorbic acid, pyrocatechol and cinnamic acid. It is possible that aloe vera acts as a kind of conductor which produces music with an orchestra of many biological active ingredients. Its thick leaves supply water for the plant to survive long periods of drought3. The antibacterial activity of aloe vera gel extract was tested using agar well diffusion technique as described by agarry et al. Proximate analysis of aloe vara leaves iosr journals. The antimicrobial activity of aloe vera extract was tested against pathogenic bacteria like staphylococcus aureus, klebisella pneumonia and li. The objective of this study was to determine and compare the antioxidant activity of aloe vera of different growth periods and their extracts with bht and r. Evaluation of antimicrobial efficacy of aloe vera and its. Aloe vera, tilapia, rats, alternate medicine, human health implications introduction aloe vera l, a member of the family lilieceae, is a popular perennial succulent plant that is cactus.
University of sarajevo, faculty of science, department of chemistry, zmaja od bosne 3335, sarajevo, bih. Figure 1 the active components of aloe include anthraquinones, chromones, polysaccharides, and enzymes. The serious health implication for human consumption of raw a. Chemical composition and biochemical activity of aloe vera. University of sarajevo, faculty of science, department of chemistry, zmaja od bosne 3335, sarajevo, bih 3 extract. Antimicrobial activity of four extracts was performed by agar well diffusion method against different bacteria and fungi. Comparative antimicrobial activities of aloe vera gel and leaf. Pdf green synthesis of copper oxide nanoparticles using. The antibacterial studies were carried out by disc diffusion technique. Aloe vera research organic aloe vera wholesale, organic. Aloe vera gel, aloe vera cream does not having major side effect but other preparation like juice, shampoo butter, having certain impediment like, diarrhea,blood electrolyte imbalance, constipation, muscle weakness, abnormal heart rhythms 7.
Antibacterial activity of leaf extracts of aloe vera. Antibacterial activity of the aloe vera gel extracts. This collection of fact sheets and other resources from the nih office of dietary supplements and other federal government sources presents information about dietary supplements and. Antihyperlipidemic activity aloe vera has been shown to prevent fatty streak development and also reduce the development of atherosclerosis through the modification of high risk factors. Dec 19, 2018 aloe is a succulent plant widely used in alternative medicine. The leaf extracts were used in the concentration of 50,100 and 150 l disc and the standard drug ciprofloxacin was used in 50 l disc concentration. Pdf antibacterial activity of aloe vera leaf gel extracts. The alcohol s extraction ethanol of aloe vera leaves gel showed highest inhibition activity on staphylococcus faecalis with inhibition zone diameter 26 millimeter compared with antibiotics. We studied the effects of aqueous, chloroform, and ethanol extracts of aloe vera gel on carrageenaninduced edema in the rat paw, and neutrophil migration into the peritoneal cavity stimulated by carrageenan. Ethanol was used for the extraction of the leaf after obtaining the gel from it. Introduction aloe vera aloe barbadensis miller is a plant, which belongs to the family of liliaceae and is mostly succulent with a whorl of elongated, pointed leaves strickland et al. Component and application aloe vera plant in medicine. Jan 09, 2019 a study assessed the antioxidant activity of aloe vera gel on colorectal mucosal biopsies. Aloe vera products contain multiple constituents with potential biological and toxicological activities, yet the active components elude definition.
The lowest content of phenolic and flavonoid compounds was observed in. The antimicrobial activity of aloe vera extract was tested against pathogenic bacteria like staphylococcus aureus, klebisella pneumonia and li and fungi like aspergillus niger and candida at a. Aloe vera, medicine plant, food additive introduction for centuries, aloe vera has been used by many different. Aloe barbadensis miller, aloe vera, has a long history of use as a topical and oral therapeutic. Aloe vera national institute of environmental health services. Aloe vera had a dosedependent inhibitory effect on reactive oxygen metabolite production, and it also inhibited the production of prostaglandin e 2 by 30% at a 1 in 50 dilution p 0. Aloe vera polysaccharide antioxidant both activity zebra. Earlier studies have reported the antiinflammatory and antibacterial properties of aloe vera. The chemistry of the plant has revealed the presence of more than 200 different biologically active substances. Aloe vera shows statistically significant antiulcer activity as well as to standard drug omeprazole.
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